The Pan-Coronavirus Panel (Pan-CoV) allows for detection and sequencing of known human and animal coronaviruses and closely related novel coronaviruses with the potential to become infectious to humans. It includes hybrid–capture oligos that span across reference genomes of multiple coronavirus strains and various known animal hosts.
When combined with Illumina RNA Prep with Enrichment, the Pan-Coronavirus Panel enables whole-genome sequencing (WGS) of 225 known human and animal coronaviruses. The targeted enrichment approach captures mutations and variants throughout the viral genome, enabling sequencing of novel coronavirus strains and detection of recombination between strains.
The panel can be used for multiple applications, including: